CIS and OpenAI launch AI cyber defense pilot to strengthen security across critical infrastructure, SLTT governments

The Center for Internet Security Inc. (CIS), in collaboration with OpenAI, announced an AI Cyber Defense Pilot designed to help U.S. State, Local, Tribal, and Territorial (SLTT) governments and critical infrastructure organizations harness the power of artificial intelligence to enhance cybersecurity and resilience.

As cyber threats become more sophisticated and widespread, foreign adversaries continue to target the nation’s critical infrastructure. At the same time, many public sector organizations and critical infrastructure operators must defend increasingly complex environments with limited resources.

The initiative will bring together government and critical infrastructure organizations, including members of the MS-ISAC community, of varying sizes, regions, and cybersecurity maturity levels to examine how AI can be applied to real-world cybersecurity challenges. The pilot program will evaluate AI’s potential to help organizations detect risks faster, better prioritize security actions, strengthen cyber hygiene, and improve overall cyber readiness.

“The services Americans rely on every day are increasingly in the crosshairs of cyber threats. At a time when defenders at the state and local government level are challenged by a growing threat landscape, AI has the potential to be a game changer,” said Brian Calkin, Chief Technology and Innovation Officer at CIS. “This pilot will help us understand how AI can help organizations make smarter decisions, respond faster, and focus on the risks that matter most. The lessons we learn can help strengthen cyber resilience for communities across the country.”